Champions league began and there were some surprises from the start. Roma was defeated in Rome from debutants CFR of Romania, Bremen played draw with Anorthosis, Shakhtar defeated Basel, Atlético destroyed PSV in the Netherlands. Champion of Europe Man.United played only 0:0 with Villarreal.
Group A
Chelsea 4 - 0 Bordeaux (Lampard 14, J. Cole 30, Malouda 82, Anelka 90+2)
Roma 1 - 2
CFR (Panucci 17, Juan Culio 27, 49)
| Rk. | Team | W | D | L | GF:GA | Points |
| 1. | Chelsea | 1 | 0 | 0 | 4:0 | 3 |
| 2. | CFR | 1 | 0 | 0 | 2:1 | 3 |
| 3. | Roma | 0 | 0 | 1 | 1:2 | 0 |
| 4. | Bordeaux | 0 | 0 | 1 | 0:4 | 0 |
Group B
Panathinaikos 0 - 2
Inter (Mancini 27, Adriano 85)
Bremen 0 - 0 Anorthosis
| Rk. | Team | W | D | L | GF:GA | Points |
| 1. | Inter | 1 | 0 | 0 | 2:0 | 3 |
| 2. | Bremen | 0 | 1 | 0 | 0:0 | 1 |
| 3. | Anorthosis | 0 | 1 | 0 | 0:0 | 1 |
| 4. | Panathinaikos | 0 | 0 | 1 | 0:2 | 0 |
Group C
Basel 1 - 2
Shakhtar (Abraham 90+3, Fernandinho 25, Jadson 45+1)
Barcelona 3 - 1 Sporting (Márquez 21, Eto'o 60(pen), Xavi Hernández 87, Tonel 72)
| Rk. | Team | W | D | L | GF:GA | Points |
| 1. | Barcelona | 1 | 0 | 0 | 3:1 | 3 |
| 2. | Shakhtar | 1 | 0 | 0 | 2:1 | 3 |
| 3. | Basel | 0 | 0 | 1 | 1:2 | 0 |
| 4. | Sporting | 0 | 0 | 1 | 1:3 | 0 |
Group D
PSV 0 - 3
Atlético (Agüero 9, 36, Maniche 54)
Marseille 1 - 2
Liverpool (Cana 23, Gerrard 26, 32(pen))
| Rk. | Team | W | D | L | GF:GA | Points |
| 1. | Atlético | 1 | 0 | 0 | 3:0 | 3 |
| 2. | Liverpool | 1 | 0 | 0 | 2:1 | 3 |
| 3. | Marseille | 0 | 0 | 1 | 1:2 | 0 |
| 4. | PSV | 0 | 0 | 1 | 0:3 | 0 |
Group E
Man.United 0 - 0 Villarreal
Celtic 0 - 0 AaB
| Rk. | Team | W | D | L | GF:GA | Points |
| 1. | Man.United | 0 | 1 | 0 | 0:0 | 1 |
| 2. | Villarreal | 0 | 1 | 0 | 0:0 | 1 |
| 3. | Celtic | 0 | 1 | 0 | 0:0 | 1 |
| 4. | AaB | 0 | 1 | 0 | 0:0 | 1 |
Group F
FC Steaua 0 - 1
BayernM. (Van Buyten 15)
Lyon 2 - 2 Fiorentina (Piquionne 73, Benzema 86, Gilardino 12, 42)
| Rk. | Team | W | D | L | GF:GA | Points |
| 1. | BayernM. | 1 | 0 | 0 | 1:0 | 3 |
| 2. | Fiorentina | 0 | 1 | 0 | 2:2 | 1 |
| 3. | Lyon | 0 | 1 | 0 | 2:2 | 1 |
| 4. | FC Steaua | 0 | 0 | 1 | 0:1 | 0 |
Group G
Porto 3 - 1 Fenerbahçe (Lisandro 10, Lucho 13, Lino 90+2, Güiza 29)
Dynamo Kyiv 1 - 1 Arsenal (Bangoura 64(pen), Gallas 88)
| Rk. | Team | W | D | L | GF:GA | Points |
| 1. | Porto | 1 | 0 | 0 | 3:1 | 3 |
| 2. | Arsenal | 0 | 1 | 0 | 1:1 | 1 |
| 3. | DynamoKyiv | 0 | 1 | 0 | 1:1 | 1 |
| 4. | Fenerbahçe | 0 | 0 | 1 | 1:3 | 0 |
Group H
Juventus 1 - 0 Zenit (Del Piero 76)
Real Madrid 2 - 0 BATE (Sergio Ramos 11, Van Nistelrooy 57)
| Rk. | Team | W | D | L | GF:GA | Points |
| 1. | RealMadrid | 1 | 0 | 0 | 2:0 | 3 |
| 2. | Juventus | 1 | 0 | 0 | 1:0 | 3 |
| 3. | Zenit | 0 | 0 | 1 | 0:1 | 0 |
| 4. | BATE | 0 | 0 | 1 | 0:2 | 0 |
