Santos FC - São Paulo FC ai prediction 21.09.2025 Série A

Preview for match Santos FC vs São Paulo FC

The upcoming clash between Santos FC and São Paulo FC promises to be a pivotal encounter in the Série A, taking place on Monday, 22nd September 2025, at 00:30. As the 24th matchday of the season unfolds, both teams find themselves in contrasting positions within the league standings. Santos FC, currently languishing in 16th place with a mere 23 points from 22 matches, has experienced a tumultuous season thus far, recording six victories, five draws, and eleven defeats. Their goal difference of 21:32 highlights their struggles, particularly in defense, while their home record of three wins, three draws, and four defeats suggests inconsistency at their Estádio Urbano Caldeira.

In stark contrast, São Paulo FC occupies a more favorable position, sitting 7th in the league with 35 points. The team has secured nine wins, eight draws, and six defeats, showcasing a more balanced performance across the season. With a goal tally of 27:23, São Paulo has demonstrated a solid defensive capability, especially when compared to Santos. However, their away form has been less impressive, with only two wins, five draws, and four defeats in away fixtures, indicating potential vulnerabilities when playing outside their home ground.

The historical context of this matchup adds an intriguing layer to the proceedings. In their last direct meeting, São Paulo triumphed with a 2-1 victory, which they will undoubtedly aim to replicate. Moreover, the head-to-head record in the last five encounters sees Santos securing two wins, while São Paulo has also claimed two victories, with one match ending in a draw. This competitive history suggests that both teams are well-acquainted with each other's strengths and weaknesses, setting the stage for a compelling encounter.

Our betting tip for the match Santos FC vs São Paulo FC

In light of the current form and standings of both teams, our betting prediction favors Santos FC to secure a home victory. The odds for a Santos win (Tip 1) stand at 2.31 with Betika, which reflects a promising opportunity for bettors looking to capitalize on their home advantage. Additionally, we advise considering the second tip: "Both teams do not score," with odds at 1.73 from 888sport. Given the defensive records of both teams, this prediction aligns well with our analysis.

Our tips

Double Chance

X2

Santos FC have drawn or lost 4 of their last 4 matches.

São Paulo FC have won or drawn 4 of their last 6 matches.

Top odds at 1xBet

Total Goals

Under 2.5

There have been under 2.5 goals scored in 3 of Santos FC's last 4 matches.

There have been under 2.5 goals scored in 5 of São Paulo FC's last 6 matches.

Top odds at 1xBet

Total Goals

Over 1.5

There have been over 1.5 goals scored in 3 of Santos FC's last 4 matches.

There have been over 1.5 goals scored in 4 of São Paulo FC's last 6 matches.

Top odds at bet365

AI prediction for the match Santos FC vs São Paulo FC

The AI forecast for this match suggests that Santos FC is positioned to emerge victorious, primarily due to their necessity to secure points for survival in the league. With their recent performance showing a slight upward trend, coupled with São Paulo's recent struggles, the AI betting tip indicates a probable scoreline of 2-1 in favor of Santos. This prediction is bolstered by the statistical analysis of both teams' attacking and defensive capabilities, underscoring the importance of this match in shaping the latter stages of the season.

Santos FC performance check

Santos FC's current form reflects a team in search of consistency. Under the guidance of head coach Juan Pablo Vojvoda, the squad has managed to secure only one win in their last five matches, accompanied by two draws and two losses. This performance has contributed to their precarious position on the league table. The team's home record has been a mixed bag, showcasing their potential but often faltering against stronger opponents. For Santos to turn their season around, a strong showing against a rival like São Paulo is crucial.

How is the current performance of São Paulo FC

São Paulo FC, coached by Hernán Crespo, has demonstrated a more robust performance this season compared to their counterparts. The team has recorded three wins in their last five matches, alongside two defeats. This form has positioned them within the top half of the league standings, providing a solid foundation as they approach the final third of the season. However, their away form raises concerns, indicating that they may struggle in hostile environments. For São Paulo to maintain their upward trajectory, securing points in this away fixture is imperative.

Head-to-head last direct meetings

In the last five direct encounters between these two teams, the competitive nature of their rivalry is evident, with Santos FC claiming two victories and São Paulo FC also winning two matches, alongside one draw. This parity suggests that neither team holds a definitive psychological edge, making this forthcoming match even more critical for both sides.

Performance last 5 matches

Over the last five matches, Santos FC has recorded one win, two draws, and two defeats, indicating a lack of momentum as they navigate through the season. Conversely, São Paulo FC has found success with three wins and two defeats, reflecting a more favorable trajectory as they aim for a top-four finish.

Performance

Santos FC

Last games

Santos FC performance of the last 3 home matches

Victories

33%

Over 2.5

66%

São Paulo FC

Last games

São Paulo FC performance of the last 7 away matches

Victories

28%

Over 2.5

28%

Last match results

In their most recent outings, Santos FC managed to secure a 1-1 draw against Atlético Mineiro, showcasing their resilience. On the other hand, São Paulo FC suffered a disappointing 0-2 defeat against LDU Quito, which may impact their confidence heading into this match.

Best odds and our betting tip

The best odds available for this match indicate that Santos FC is a viable option for bettors looking to capitalize on their home advantage. With Tip 1 available at 2.31 at Betika, and the odds for both teams not to score at 1.73 from 888sport, bettors can find value in these offerings. It is advisable to explore various betting sites for the most favorable odds, ensuring that you secure the best possible return on your wagers.

Conclusion

In conclusion, Santos FC appears to be in a favorable position to secure a home victory against São Paulo FC. Their need for points in the relegation battle, coupled with São Paulo's recent away struggles, positions the home side as the favorites in this encounter. As both teams strive for critical points in the Serie A, the match is likely to be competitive and crucial for their respective aspirations.

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